A pixel driving method is provided and the method includes following steps: acquiring a pixel signal of each unit pixel in a pixel block, acquiring a first average pixel signal of the pixel block according to the pixel signal of each of the unit pixels in the pixel block, and if a signal determination interval corresponding to the first average pixel signal is a first-type interval, determining that the pixel signal of the pixel block meets a first condition; and loading first-type gray-scale signals to a part of unit pixels of the pixel block and loading second-type gray-scale signals to the remaining unit pixels of the pixel block based on a preset rule. The display quality is improved by controlling the unit pixel proportion loaded with the first-type gray-scale signal and the second-type gray-scale signal and reducing the difference among pixel signals.