Invention Grant
- Patent Title: Method for determining lymphoma type and providing treatment
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Application No.: US16713528Application Date: 2019-12-13
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Publication No.: US11646099B2Publication Date: 2023-05-09
- Inventor: Louis M. Staudt , Christian Steidl , Anja Mottok , George W. Wright , David William Scott , Lisa M. Rimsza , Andreas Rosenwald , Randy Gascoyne , Timothy Greiner , Dennis Weisenburger , Erlend B. Smeland , Jan Delabie , Elias Campo Guerri , German Ott , Rita Braziel , Elaine S. Jaffe , Kai Fu , Wing C. Chan , Joo Song , James R. Cook
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services , British Columbia Cancer Agency Branch , Mayo Foundation for Medical Education and Research , Julius-Maximilians-University of Würzburg , Board of Regents of the University of Nebraska , Oslo University Hospital HF , Hospital Clinic de Barcelona , Universitat de Barcelona , Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS) , Robert Bosch Gesellschaft fuer medizinische Forschung mbH , Oregon Health & Science University , City of Hope , The Cleveland Clinic Foundation
- Applicant Address: US MD Bethesda
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,British Columbia Cancer Agency,Mayo Foundation for Medical Education and Research,Julius-Maximilians-University of Würzburg,Boatd of Regents of the University of Nebraska,Oslo University Hospital HF,Hospital Clinic de Barcelona,Universitat de Barceloa,Institut D'Investigacions Biomédiques Pi I Sunyer (IDIBAPS),Robert Bosch Gesellschaft feuer medizinische Forshung mbH,Oregon Health & Science University,City of Hope,The Cleveland Clinic Foundation
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,British Columbia Cancer Agency,Mayo Foundation for Medical Education and Research,Julius-Maximilians-University of Würzburg,Boatd of Regents of the University of Nebraska,Oslo University Hospital HF,Hospital Clinic de Barcelona,Universitat de Barceloa,Institut D'Investigacions Biomédiques Pi I Sunyer (IDIBAPS),Robert Bosch Gesellschaft feuer medizinische Forshung mbH,Oregon Health & Science University,City of Hope,The Cleveland Clinic Foundation
- Current Assignee Address: US MD Bethesda; CA Vancouver; US MN Rochester; DE Würuzburg; US NE Lincoln; NO Oslo; ES Barcelona; ES Barcelona; ES Barcelona; DE Stuttgart; US OR Portland; US CA Duarte; US OH Cleveland
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: G01N33/48
- IPC: G01N33/48 ; G16B5/00 ; G16B25/10 ; C12Q1/6886
Abstract:
In embodiments of the invention, the invention provides a method for distinguishing between lymphoma types based on gene expression measurements. In embodiments, the invention distinguishes between PMBCL and DLBCL based on gene expression signatures, and can further distinguish between DLBCL subtypes. In embodiments of the invention, the distinctions are used in methods of treatment.
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