A digital phase-locked loop (PLL) includes a time-to-digital converter (TDC) and a digitally controlled oscillator (DCO). The DCO generates a PLL clock signal and various sampling clock signals that are mesochronous. The TDC samples a phase difference between a reference clock signal and a frequency-divided version of the PLL clock signal based on the sampling clock signals and various enable signals. The enable signals are generated based on a calibration of the digital PLL. Each enable signal is associated with a sampling clock signal and indicates whether the associated sampling clock signal is to be utilized for sampling the phase difference. Further, the TDC generates control data indicative of the sampled phase difference. The DCO generates the PLL clock signal and the sampling clock signals based on the control data until the digital PLL is in a phase-locked state.