Invention Grant
- Patent Title: Methods for the treatment of myeloid derived suppressor cells related disorders
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Application No.: US16069436Application Date: 2017-01-11
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Publication No.: US11648220B2Publication Date: 2023-05-16
- Inventor: Sohail Tavazoie , Masoud Tavazoie
- Applicant: The Rockefeller University
- Applicant Address: US NY New York
- Assignee: The Rockefeller University
- Current Assignee: The Rockefeller University
- Current Assignee Address: US NY New York
- Agency: Fox Rothschild LLP
- International Application: PCT/US2017/012906 2017.01.11
- International Announcement: WO2017/123568A 2017.07.20
- Date entered country: 2018-07-11
- Main IPC: A61K31/195
- IPC: A61K31/195 ; A61K38/14 ; A61P31/12 ; A61P31/04 ; A61P35/00 ; A61K31/4174 ; A61K31/675 ; A61K45/06
Abstract:
The invention features methods of treating disorders related to increased levels of myeloid derived suppressor cells such as cancer or infections. The disclosure also provides methods of treating cancer including combinations of LXRβ agonists and immunotherapies such as PD1 inhibitors, PDL1 inhibitors, and adoptive T-cell transfer therapy.
Public/Granted literature
- US20190029984A1 METHODS FOR THE TREATMENT OF MYELOID DERIVED SUPPRESSOR CELLS RELATED DISORDERS Public/Granted day:2019-01-31
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