Invention Grant
![Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling](/docs/US/2023-05-16/US11648254B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling
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Application No.: US17685370Application Date: 2022-03-02
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Publication No.: US11648254B2Publication Date: 2023-05-16
- Inventor: Baogen Wu , Xiangzhu Wang , Xiaoming Li , Zhiyong Chen , Pingda Ren , Yi Liu
- Applicant: Kumquat Biosciences Inc.
- Applicant Address: US CA San Diego
- Assignee: Kumquat Biosciences Inc.
- Current Assignee: Kumquat Biosciences Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D487/04 ; C07D471/04 ; A61K45/06 ; A61K31/5377 ; A61K31/506 ; A61P35/00 ; A61K31/541
![Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling](/abs-image/US/2023/05/16/US11648254B2/abs.jpg.150x150.jpg)
Abstract:
The present disclosure provides compounds represented by Formula (I-1):
and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.
and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.
Public/Granted literature
- US20230064360A1 HETEROCYCLES AND USES THEREOF Public/Granted day:2023-03-02
Information query
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