Invention Grant
- Patent Title: Human kynureninase enzymes and uses thereof
-
Application No.: US16385562Application Date: 2019-04-16
-
Publication No.: US11648272B2Publication Date: 2023-05-16
- Inventor: George Georgiou , Everett Stone , John Blazeck , Christos Karamitros
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61K47/60 ; A61P35/00 ; A61K38/46 ; C07K14/725 ; C07K16/28
Abstract:
Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids.
Public/Granted literature
- US20190350975A1 HUMAN KYNURENINASE ENZYMES AND USES THEREOF Public/Granted day:2019-11-21
Information query
IPC分类:
