Invention Grant
- Patent Title: Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
-
Application No.: US17817232Application Date: 2022-08-03
-
Publication No.: US11648278B2Publication Date: 2023-05-16
- Inventor: Seth Wardell , James Bender , Michael T. Lotze
- Applicant: Iovance Biotherapeutics, Inc.
- Applicant Address: US CA San Carlos
- Assignee: Iovance Biotherapeutics, Inc.
- Current Assignee: Iovance Biotherapeutics, Inc.
- Current Assignee Address: US CA San Carlos
- Agency: Morgan, Lewis & Bockius LLP
- The original application number of the division: US15863634 2018.01.05
- Main IPC: A61K35/17
- IPC: A61K35/17 ; C12N5/0783 ; A61K38/20 ; A61K31/675 ; A61K31/7076 ; A61P35/00 ; A61K9/00 ; A01N1/02 ; C12N5/078 ; A61K38/21 ; A61K39/00
Abstract:
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
Public/Granted literature
- US11998568B2 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy Public/Granted day:2024-06-04
Information query
IPC分类:
