The present disclosure relates to an application system with a cartridge having at least one container with a respective outlet, and a closure element that can sealingly close the outlet of the at least one container when the cartridge is in the delivery state. When in the storage state, the cartridge sealingly closes the closure element. When the cartridge is in the state of use, the closure element can be removed therefrom and an accessory can be connected to the outlet of the at least one container. According to the invention, the cartridge or the closure element comprises, in the delivery state, a connecting element which cannot be removed without being damaged, and the cartridge or the closure element, in the storage state, is connected via a connecting element that cannot be removed without being damaged, to a closure element or the cartridge.