Invention Grant
- Patent Title: Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease
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Application No.: US17221209Application Date: 2021-04-02
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Publication No.: US11649227B2Publication Date: 2023-05-16
- Inventor: Erin Danielle Anderson , Sean Douglas Aronow , Nicholas A. Boyles , Markus K. Dahlgren , Shulu Feng , Aleksey I. Gerasyuto , Eugene R. Hickey , Thomas Combs Irvin , Edward A. Kesicki , Anke Klippel-Giese , Jennifer Lynn Knight , Gabrielle R. Kolakowski , Manoj Kumar , Katelyn Frances Long , Christopher Glenn Mayne , David L. McElligott , Johnathan Alexander McLean , Loredana Puca , Kannan Karukurichi Ravi , Daniel Lee Severance , Michael Brian Welch , Tien Widjaja
- Applicant: Petra Pharma Corporation
- Applicant Address: US NY New York
- Assignee: Petra Pharma Corporation
- Current Assignee: Petra Pharma Corporation
- Current Assignee Address: US NY New York
- Agent Joseph Pletcher
- Main IPC: C07D405/04
- IPC: C07D405/04 ; C07D405/14 ; C07D491/056
Abstract:
The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I):
or a prodrug, solvate, enantiomer, stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, W, X, Y, s, and Ring A are as described herein.
or a prodrug, solvate, enantiomer, stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, W, X, Y, s, and Ring A are as described herein.
Public/Granted literature
- US20220372023A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Public/Granted day:2022-11-24
Information query
