Invention Grant
- Patent Title: Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
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Application No.: US16881650Application Date: 2020-05-22
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Publication No.: US11649294B2Publication Date: 2023-05-16
- Inventor: Jong Seo Lee , Kyu Tae Kim , Young Ha Lee , In Sik Hwang , Bong Kook Ko , Eunji Choi , You-Sun Kim , Jeongmin Kim , Miyoung Jung , Hoyong Lim , Sungyoo Cho
- Applicant: GC CELL CORPORATION
- Applicant Address: KR Gyeonggi-do
- Assignee: GC Cell Corporation
- Current Assignee: GC Cell Corporation
- Current Assignee Address: KR Gyeonggi-do
- Agency: Fish & Richardson P.C.
- Priority: KR 20170151841 2017.11.14
- Main IPC: C07K16/32
- IPC: C07K16/32 ; C07K14/705 ; A61P35/00 ; A61K38/17 ; C12N5/0783
Abstract:
The present disclosure relates to a novel anti-HER2 antibody or an antigen-binding fragment thereof used in the prevention or treatment of cancer, a chimeric antigen receptor including the same, and uses thereof. The antibody of the present disclosure is an antibody that specifically binds to HER2 which is highly expressed in cancer cells (particularly, breast cancer or gastric cancer cells), and binds to an epitope that is different from an epitope to which trastuzumab binds.
Public/Granted literature
- US2646462A Color television image reproducing system Public/Granted day:1953-07-21
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