Biomarker for detecting a possible incompatability with respect to metal implants
Abstract:
A method to predict an increased risk of a greater susceptibility to a metal implant sensitivity in a test person. The method includes providing an isolated sample with a genetic material of the test person, and examining a single nucleotide polymorphism rs1143627









SEQ ID NO: 1



AGCCTCCTACTTCTGCTTTTGAAAGC[C/T]ATAAAA







ACAGCGAGGGAGAACTGG, 






in a gene coding for interleukin 1 beta and ascertaining whether a C is present at a position of the single nucleotide polymorphism, and/or examining a VNTR polymorphism rs2234663 with the repeat










SEQ ID NO: 2



ATCCTGGGGAAAGTGAGGGAAATATGGACATCACATGGAACAACAT






CCAGGAGACTCAGGCCTCTAGGAGTAACTGGGTAGTGTGC,






in a gene coding for a IL1 receptor antagonist, IL1-RN and ascertaining whether the repeat is present five times.
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