Invention Grant
- Patent Title: DNA methylation and mutational analysis methods for bladder cancer surveillance
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Application No.: US16612926Application Date: 2018-05-17
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Publication No.: US11649506B2Publication Date: 2023-05-16
- Inventor: Margarita Lopatin , Athanasios Tsiatis , Christopher N. Silk , David P. Miller , Michael Crager , Phillip Febbo , Dejan Knezevic
- Applicant: Genomic Health, Inc.
- Applicant Address: US CA Redwood City
- Assignee: Genomic Health, Inc.
- Current Assignee: Genomic Health, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: McNeill Baur PLLC
- International Application: PCT/US2018/033146 2018.05.17
- International Announcement: WO2018/213550A 2018.11.22
- Date entered country: 2019-11-12
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/04 ; C12Q1/6886 ; A61P35/00

Abstract:
The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations. In some embodiments, analysis results are correlated with clinical outcome measures such as risk of bladder cancer recurrence.
Public/Granted literature
- US20200165686A1 DNA Methylation and Mutational Analysis Methods for Bladder Cancer Surveillance Public/Granted day:2020-05-28
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