An air-wall room system, suspended from a room ceiling, having a compressed air discharge duct. The air discharge duct is used for circulating compressed air into a hollow, four sided, upper air-wall frame with air openings. The air from the upper air-wall frame is circulated into a work space. The hollow upper air-wall frame includes air discharge ports for creating an air-wall. The air-wall, similar to a curtain, prevents toxic gases from escaping outside the work space. Corners of the upper air-wall frame are attached to vertical frame members. A bottom of the vertical frame members is attached to corners of a hollow, four sided, lower air-wall frame. The lower air-wall frame includes vacuum ports for receiving the bottom of the air-wall. A side of the lower air-wall frame is connected to a vacuum air exhaust duct. The air exhaust duct is used for drawing a vacuum in the hollow lower air-wall frame and exhausting the air-wall out a vacuum air exhaust duct.