Systems, methods and apparatus of intelligent write-amplification reduction for data storage devices configured on autonomous vehicles. For example, a data storage device of a vehicle includes: one or more storage media components; a controller configured to store data into and retrieve data from the one or more storage media components according to commands received in the data storage device; an address map configured to map between: logical addresses specified in the commands received in the data storage device, and physical addresses of memory cells in the one or more storage media components; and an artificial neural network configured to receive, as input and as a function of time, operating parameters indicative a data access pattern, and generate, based on the input, a prediction to determine an optimized data placement scheme. The controller is configured to adjust the address map according to the optimized data placement scheme.