The present disclosure relates to an automatically adjustable smart shelf, a cargo storing method, and an unmanned logistics system. The automatically adjustable smart shelf includes a shelf outer frame and a control unit. A first movable shelf layer and a second movable shelf layer provided on the shelf outer frame and respectively movable along a first direction and a second direction intersecting with each other. A control unit can control the first movable shelf layer and the second movable shelf layer to move along the first direction and the second direction respectively, so as to form various sizes of storage space for storing various cargos accordingly.