Invention Grant
- Patent Title: 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same
-
Application No.: US16982559Application Date: 2019-03-20
-
Publication No.: US11654137B2Publication Date: 2023-05-23
- Inventor: Adegboyega K. Oyelere , Verjine Khodaverdian , Subhasish Tapadar
- Applicant: Georgia Tech Research Corporation
- Applicant Address: US GA Atlanta
- Assignee: Georgia Tech Research Corporation
- Current Assignee: Georgia Tech Research Corporation
- Current Assignee Address: US GA Atlanta
- Agency: Troutman Pepper Hamilton Sanders LLP
- Agent Ryan A. Schneider; Sarah M L Wilkening
- International Application: PCT/US2019/023127 2019.03.20
- International Announcement: WO2019/183197A 2019.09.26
- Date entered country: 2020-09-19
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61P35/00 ; A61K45/06 ; C07D401/06
Abstract:
Compositions and methods for inhibiting histone lysine demethylases are provided. Several new DFP-based KDM inhibitors which alter the velocity of HP1-mediated heterochromatin gene repression are provided.
Public/Granted literature
- US20210000811A1 3-(HYDROXY)-PYRIDIN-4(1H)-ONE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2021-01-07
Information query
IPC分类:
