Invention Grant
- Patent Title: Oxadiazole transient receptor potential channel inhibitors
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Application No.: US16903020Application Date: 2020-06-16
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Publication No.: US11655245B2Publication Date: 2023-05-23
- Inventor: Jack Alexander Terrett , Huifen Chen , Lea Constantineau-Forget , Robin Larouche-Gauthier , Luce Lépissier , Francis Beaumier , Martin Déry , Chantal Grand-Maître , Claudio Sturino , Matthew Volgraf , Elisia Villemure
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Jelena Libby
- The original application number of the division: US16355352 2019.03.15
- Main IPC: A61K31/427
- IPC: A61K31/427 ; A61P11/00 ; A61P23/00 ; A61P25/00 ; A61P29/00 ; C07D513/04 ; C07D473/30 ; C07D487/04 ; C07D498/04 ; C07D471/04 ; C07D413/14
Abstract:
The invention relates to methods of using compounds formula I:
and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
Public/Granted literature
- US20200308161A1 OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS Public/Granted day:2020-10-01
Information query
IPC分类:
