Invention Grant
- Patent Title: Use of novel miRNA-binding site cassettes for antigen-presenting cell detargeting of transgene expression by rAAV gene therapy vectors
-
Application No.: US17581306Application Date: 2022-01-21
-
Publication No.: US11655483B2Publication Date: 2023-05-23
- Inventor: Guangping Gao , Phillip Tai , Manish Muhuri , Wei Zhan
- Applicant: University of Massachusetts
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N15/86
- IPC: C12N15/86 ; A61K31/7088 ; C12N15/113
Abstract:
The disclosure, in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.
Public/Granted literature
Information query
IPC分类:
