Transaction-enabled methods for providing provable access to a distributed ledger with a tokenized instruction set for biological production processes are described. A method may include accessing a distributed ledger comprising an instruction set for a biological production process and tokenizing the instruction set. The method may further include interpreting an instruction set access request and, in response to the access request, providing a provable access to the instruction set. The method may further include providing commands to a production tool of the biological production process in response to the instruction set access request and recording the transaction on the distributed ledger.