A semiconductor device includes a first gate line and a second gate line extending along a first direction, a third gate line extending along a second direction and between and directly contacting the first gate line and the second gate line, a drain region adjacent to one side of the third gate line, a fourth gate line extending along the second direction and between and directly contacting the first gate line and the second gate line, and a first metal interconnection extending along the second direction between the third gate line and the fourth gate line. Preferably, the third gate line includes a first protrusion and the fourth gate line includes a second protrusion.