A system for structured light depth computation using single photon avalanche diodes (SPADs) is configurable to, over a frame capture time period, selectively activate the illuminator to perform interleaved structured light illumination operations. The interleaved structured light illumination operations comprise alternately emitting at least a first structured light pattern from the illuminator and emitting at least a second structured light pattern from the illuminator. The system is also configurable to, over the frame capture time period, perform a plurality of sequential shutter operations to configure each SPAD pixel of the SPAD array to enable photon detection. The plurality of sequential shutter operations generates, for each SPAD pixel of the SPAD array, a plurality of binary counts indicating whether a photon was detected during each of the plurality of sequential shutter operations.