Invention Grant
- Patent Title: Biodegradable block copolymer drug delivery composition
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Application No.: US16631586Application Date: 2018-07-17
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Publication No.: US11666527B2Publication Date: 2023-06-06
- Inventor: Christophe Roberge , Anthony Rech , Jean-Manuel Cros , Myriam Abbassi , Adolfo López-Noriega , Lea Pebrel , Audrey Petit , Juliette Serindoux
- Applicant: MEDINCELL , Christophe Roberge , Anthony Rech , Jean-Manuel Cros
- Applicant Address: FR Jacou
- Assignee: MEDINCELL,Christophe Roberge,Anthony Rech,Jean-Manuel Cros
- Current Assignee: MEDINCELL,Christophe Roberge,Anthony Rech,Jean-Manuel Cros
- Current Assignee Address: FR Jacou; FR Jacou; FR Jacou; FR Jacou
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/EP2018/069442 2018.07.17
- International Announcement: WO2019/016236A 2019.01.24
- Date entered country: 2020-01-16
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K31/167 ; A61K31/5415 ; A61K31/7048 ; A61K47/34 ; C08G63/664 ; A61K31/445 ; A61K31/519 ; A61K38/12 ; A61K9/20

Abstract:
Provided is a biodegradable drug delivery composition comprising: (i) a mixture of at least three different block copolymers, wherein each block copolymer is: (a) a biodegradable triblock copolymer having the formula: Av-Bw-Ax wherein A is a polyester and B is polyethylene glycol and v and x are from 1 to 3,000 and w is from 3 to 300 and v=x or v≠x; or (b) a biodegradable diblock copolymer having the formula: Cy-Az wherein A is a polyester and C is an end-capped polyethylene glycol and y=2 to 250 and z=1 to 3,000; and wherein the mixture comprises at least one (a) and at least one (b); and the weight ratio between (a) and (b) is 1:19 to 5:1; and for at least one of the copolymers according to (a) or (b) A is poly(lactic-co-glycolic acid) (PLGA); and (ii) at least one pharmaceutically active ingredient.
Public/Granted literature
- US20200179518A1 PHARMACEUTICAL COMPOSITION Public/Granted day:2020-06-11
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