Invention Grant
- Patent Title: Formulations and pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
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Application No.: US16859514Application Date: 2020-04-27
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Publication No.: US11666566B2Publication Date: 2023-06-06
- Inventor: Andreas Sommer , Chengzhi Zhang , John Carter , John Charles Arthur , Margaret Bradbury , Thomas George Gant , Manouchehr Shahbaz
- Applicant: AUSPEX PHARMACEUTICALS, INC.
- Applicant Address: US NJ Parsippany
- Assignee: Auspex Pharmaceuticals, Inc.
- Current Assignee: Auspex Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Parsippany
- Agency: BakerHostetler
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K9/28 ; A61K47/38 ; A61P25/14 ; A61K31/473 ; A61K9/00 ; A61K9/16 ; A61K9/48 ; A61K9/50 ; A61K31/4745 ; A61K45/06 ; C07D455/06
Abstract:
The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.
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