Invention Grant
- Patent Title: Pharmaceutical combinations comprising a histone deacetylase inhibitor and a BCL-2 inhibitor and methods of use thereof
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Application No.: US16344873Application Date: 2017-11-03
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Publication No.: US11666568B2Publication Date: 2023-06-06
- Inventor: Nathan Moore , Chengyin Min
- Applicant: ACETYLON PHARMACEUTICALS, INC.
- Applicant Address: US MA Boston
- Assignee: ACETYLON PHARMACEUTICALS, INC.
- Current Assignee: ACETYLON PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Boston
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque
- International Application: PCT/US2017/059927 2017.11.03
- International Announcement: WO2018/085652A 2018.05.11
- Date entered country: 2019-04-25
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61P35/02 ; A61K31/635 ; C07D239/42
Abstract:
The present disclosure relates to a pharmaceutical combination comprising (a) a histone deacetylase 6 inhibitor and (b) a BCL-2 inhibitor, including combined preparations and pharmaceutical compositions thereof; uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer in a subject comprising administering a therapeutically effective amount of such combination.
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