Invention Grant
- Patent Title: MLKL inhibitors
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Application No.: US16550316Application Date: 2019-08-26
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Publication No.: US11666577B2Publication Date: 2023-06-06
- Inventor: Zhiyuan Zhang , Xiaodong Wang , Shaoqiang Huang , Bo Yan , Lei Liu , Huayi Wang , Jianguang Han , Zhi Huang , Weiye Cao
- Applicant: National Institute of Biological Sciences, Beijing
- Applicant Address: CN Beijing
- Assignee: National Institute of Biological Sciences, Beijing
- Current Assignee: National Institute of Biological Sciences, Beijing
- Current Assignee Address: CN Beijing
- Agent Richard Aron Osman
- Main IPC: A61K31/522
- IPC: A61K31/522 ; A61P25/00 ; A61K31/5377
Abstract:
The invention provides compounds that inhibit human MLKL, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition.
Public/Granted literature
- US20190381052A1 MLKL Inhibitors Public/Granted day:2019-12-19
Information query
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