Invention Grant
- Patent Title: Double auxotrophic
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Application No.: US17268789Application Date: 2019-08-15
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Publication No.: US11666648B2Publication Date: 2023-06-06
- Inventor: William R. Jacobs, Jr. , Sangeeta Tiwari
- Applicant: Albert Einstein College of Medicine
- Applicant Address: US NY Bronx
- Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee Address: US NY Bronx
- Agency: Cantor Colburn LLP
- International Application: PCT/US2019/046703 2019.08.15
- International Announcement: WO2020/037148A 2020.02.20
- Date entered country: 2021-02-16
- Main IPC: A61K39/04
- IPC: A61K39/04 ; A61P37/04 ; C12N15/52 ; C12Q1/6897 ; A61K39/00
Abstract:
Provided are attenuated strains of M. tuberculosis and M. bovis BCG which are double auxotrophic mutants with genes knocked out in the biosynthetic pathways for arginine and methionine, and compositions and methods of use thereof.
Public/Granted literature
- US20210170008A1 DOUBLE AUXOTROPHIC MYCOBACTERIUM AND USES THEREOF Public/Granted day:2021-06-10
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