Invention Grant
- Patent Title: RNA-guided systems for in vivo gene editing
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Application No.: US16834339Application Date: 2020-03-30
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Publication No.: US11666665B2Publication Date: 2023-06-06
- Inventor: Amy J. Wagers , Mohammadsharif Tabebordbar , Wei Leong Chew , George M. Church
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Banner & Witcoff, Ltd.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N9/22 ; C12N15/11 ; C12N15/86 ; C12N15/10 ; C12N15/90
Abstract:
Methods of editing target nucleic acids are provided using a guide RNA and a Cas9 protein to excise exons in a target gene and where the edited gene is expressed to produce a truncated polypeptide.
Public/Granted literature
- US20200289669A1 RNA-Guided Systems for In Vivo Gene Editing Public/Granted day:2020-09-17
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