A disposable receptacle useful with an infant feeding system, including a pliable pouch. The pliable pouch may have a single compartment, or a pair of compartments wherein a first compartment is filled with powdered formula, and a second compartment is filled with distilled water. When compartmentalized, the compartments are separated by a burst seal designed to fail upon subjection to pressure of between about 1-3 lbs. The receptacles include a cylindrical fitment with a one-way valve removably positioned therewithin. A top seal of the pliable pouch is secured about the body of the fitment. The receptacles may be used with an infant feeding system having a support disc with an aperture to receive and secure the fitment, and a nipple having an internal chamber sized and configured to tightly and removably receive a portion of the fitment. The infant feeding system may optionally include a bottle and a securing ring.