Invention Grant
- Patent Title: Modulators of 5′-nucleotidase, ecto and the use thereof
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Application No.: US17206896Application Date: 2021-03-19
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Publication No.: US11667662B2Publication Date: 2023-06-06
- Inventor: Laurent Pierre Paul Debien , Juan Carlos Jaen , Jaroslaw Kalisiak , Kenneth V. Lawson , Manmohan Reddy Leleti , Erick Allen Lindsey , Dillon Harding Miles , Eric Newcomb , Jay Patrick Powers , Brandon Reid Rosen , Ehesan Ui Sharif
- Applicant: ARCUS BIOSCIENCES, INC.
- Applicant Address: US CA Hayward
- Assignee: ARCUS BIOSCIENCES, INC.
- Current Assignee: ARCUS BIOSCIENCES, INC.
- Current Assignee Address: US CA Hayward
- Agency: Sheppard Mullin Richter & Hampton LLP
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H19/23 ; A61K31/7076 ; C07H19/16 ; C07H19/20 ; C07H19/207 ; C07F9/6561 ; C07H19/04 ; A61K31/706 ; A61K45/06 ; A61K31/7052 ; A61K31/7064 ; C07H19/14

Abstract:
Compounds that modulate the conversion of AMP to adenosine by 5′-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5′-nucleotidase, ecto is also provided.
Public/Granted literature
- US20210371449A1 MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF Public/Granted day:2021-12-02
Information query
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