Invention Grant
- Patent Title: RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
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Application No.: US16680101Application Date: 2019-11-11
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Publication No.: US11667915B2Publication Date: 2023-06-06
- Inventor: Tod M. Woolf , Joanne Kamens , William Salomon , Anastasia Khvorova
- Applicant: Phio Pharmaceuticals Corp.
- Applicant Address: US MA Marlborough
- Assignee: Phio Pharmaceuticals Corp.
- Current Assignee: Phio Pharmaceuticals Corp.
- Current Assignee Address: US MA Marlborough
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N15/11
- IPC: C12N15/11
Abstract:
The present invention relates to RNAi constructs and their use in gene silencing. RNAi constructs associated with the invention contain a double stranded region connected to a single stranded region of phosphorothioate modified nucleotides.
Public/Granted literature
- US20200308578A1 RNA DUPLEXES WITH SINGLE STRANDED PHOSPHOROTHIOATE NUCLEOTIDE REGIONS FOR ADDITIONAL FUNCTIONALITY Public/Granted day:2020-10-01
Information query
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