Invention Grant
- Patent Title: Methods and compositions for improved expression of recombinant proteins
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Application No.: US16644444Application Date: 2018-09-04
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Publication No.: US11667944B2Publication Date: 2023-06-06
- Inventor: Frederick R. Blattner , Robert E. Novy , David A. Frisch , Charles Landry , Hyunsic Choi , Eric A. Steffen , John Brandon
- Applicant: SCARAB GENOMICS LLC
- Applicant Address: US WI Madison
- Assignee: SCARAB GENOMICS, LLC
- Current Assignee: SCARAB GENOMICS, LLC
- Current Assignee Address: US WI Madison
- Agency: Much Shelist, PC
- Agent Christopher M Cabral
- International Application: PCT/US2018/049422 2018.09.04
- International Announcement: WO2019/050872A 2019.03.14
- Date entered country: 2020-03-04
- Main IPC: C12P21/02
- IPC: C12P21/02 ; C12N9/18 ; C12N1/21 ; C12N15/70 ; C12P21/06 ; C07K14/21 ; C07K14/285 ; C07K14/34 ; C12N1/20

Abstract:
Provided herein are methods for the improved production of periplasmic-targeted recombinant proteins in E. coli host strains. Also provided are E. coli host strains with improved capacity for producing recombinant proteins.
Public/Granted literature
- US20200318150A1 Methods and Compositions for Improved Expression of Recombinant Proteins Public/Granted day:2020-10-08
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