Invention Grant
- Patent Title: Protective surface coatings for flow cells
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Application No.: US15969562Application Date: 2018-05-02
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Publication No.: US11667969B2Publication Date: 2023-06-06
- Inventor: Sean M. Ramirez , Brian D. Mather , Edwin Li , Sojeong Moon , Innsu Daniel Kim , Alexandre Richez , Ludovic Vincent , Xavier von Hatten , Hai Quang Tran , Maxwell Zimmerley , Julia Morrison , Gianluca Andrea Artioli , Krystal Sly , Hayden Black , Lewis J. Kraft , Hong Xie , Wei Wei , Ryan Sanford
- Applicant: ILLUMINA, INC. , ILLUMINA CAMBRIDGE LIMITED , ILLUMINA SINGAPORE PTE. LTD.
- Applicant Address: US CA San Diego
- Assignee: Illumina, Inc.,Illumina Cambridge Limited,Illumina Singapore Pte. Ltd.
- Current Assignee: Illumina, Inc.,Illumina Cambridge Limited,Illumina Singapore Pte. Ltd.
- Current Assignee Address: US CA San Diego; GB Cambridge; SG Helios
- Agency: Dierker & Kavanaugh, P, C.
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12Q1/6874 ; C12Q1/6806

Abstract:
An example of a method includes providing a substrate with an exposed surface comprising a first chemical group, wherein the providing optionally comprises modifying the exposed surface of the substrate to incorporate the first chemical group; reacting the first chemical group with a first reactive group of a functionalized polymer molecule to form a functionalized polymer coating layer covalently bound to the exposed surface of the substrate; grafting a primer to the functionalized polymer coating layer by reacting the primer with a second reactive group of the functionalized polymer coating layer; and forming a water-soluble protective coating on the primer and the functionalized polymer coating layer. Examples of flow cells incorporating examples of the water-soluble protective coating are also disclosed herein.
Public/Granted literature
- US20180327832A1 PROTECTIVE SURFACE COATINGS FOR FLOW CELLS Public/Granted day:2018-11-15
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