Invention Grant
- Patent Title: Biomarkers of disease
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Application No.: US16615687Application Date: 2018-05-22
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Publication No.: US11668715B2Publication Date: 2023-06-06
- Inventor: Elin Gray , Pauline Zaenker , Mel Ziman , Johnny Su Hau Lo
- Applicant: Edith Cowan University
- Applicant Address: AU Joondalup
- Assignee: Edith Cowan University
- Current Assignee: Edith Cowan University
- Current Assignee Address: AU Western
- Agency: Morgan, Lewis & Bockius LLP
- Priority: AU 17901921 2017.05.22
- International Application: PCT/AU2018/050492 2018.05.22
- International Announcement: WO2018/213877A 2018.11.29
- Date entered country: 2019-11-21
- Main IPC: G01N33/00
- IPC: G01N33/00 ; G01N33/574 ; G01N33/564

Abstract:
The present invention relates to methods for the diagnosis and treatment of melanoma. In particular, the invention relates to methods for the diagnosis and treatment of early stage melanoma by measuring the expression of one or more autoantibodies selected from the group consisting of anti-ZBTB7B, anti-PRKCH, anti-TP53, anti-PCTK1, anti-PQBP1, anti-UBE2V1, anti-IRF4, anti-MAPK8_tv2, anti-MSN and anti-TPM1. Further, the present invention relates to kits comprising one or more reagents and/or devices when used in performing the methods for the diagnosis and treatment of melanoma.
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