Invention Grant
- Patent Title: Automated dissolution/permeation testing system
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Application No.: US16913560Application Date: 2020-06-26
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Publication No.: US11668723B2Publication Date: 2023-06-06
- Inventor: Luke Lee
- Applicant: Logan Instruments Corporation
- Applicant Address: US NJ Somerset
- Assignee: Logan Instruments Corporation
- Current Assignee: Logan Instruments Corporation
- Current Assignee Address: US NJ Somerset
- Agent Brian Roffe
- Main IPC: G01N35/00
- IPC: G01N35/00 ; G01N35/08

Abstract:
Combined dissolution rate and permeation rate testing apparatus includes temperature-controllable testing cell units arranged on a housing frame. Each testing cell unit includes a donor chamber receivable of dissolution media, a receptor chamber receivable of bodily fluid, gaskets that retain a membrane between the two chambers, and controllable mixers that mix the fluid in the receptor chamber. A flow control arrangement operatively circulates dissolution media through the donor chamber and enables sampling of the dissolution media. Another flow control arrangement operatively circulates bodily fluid through the receptor chamber. An analysis unit analyzes dissolution media removed from the donor chamber and bodily fluid removed from the receptor chamber to provide data about dissolution of a pharmaceutical product dissolved in the dissolution media and permeation of the pharmaceutical product through the membrane into the bodily fluid.
Public/Granted literature
- US20210011038A1 Automated Dissolution/Permeation Testing System Public/Granted day:2021-01-14
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