The technology disclosed herein enables a processor to receive program code comprising a plurality of program code instructions generated by a compiler in view of source code, identify, among the program code instructions, one or more optimizable instructions, wherein at least one of the optimizable instructions is associated with an execution characteristic, and the execution characteristic is associated with an optimization decision, identify a profiling instruction location associated with the at least one of the optimizable instructions, and add a profiling instruction to the program code at the profiling instruction location. The at least one profiling instruction comprises a profiling identifier, and causes the processing device to: generate a profiling information item in view of the execution characteristic of the optimizable instructions, and store the profiling information item in a persistent memory region at a memory location corresponding to the profiling identifier.