The present invention relates to a cable lead-out system, configured to route at least one cable from inside of a device to outside of the device, wherein the cable lead-out system comprises: a first pressing piece having at least one through hole for leading out the cable; a second pressing piece having at least one through hole for leading out the cable; and a seal having a base sandwiched between the first pressing piece and the second pressing piece with two opposite sides thereof, and being deformable when being pressed by the first pressing piece and the second pressing piece, having the base comprising at least one through hole for leading out the cable, and at least one protrusion that protrudes from at least one of the two sides of the base, and each of the at least one protrusion being disposed around a through hole of the base, whereby the through hole of the base passes throughout the protrusion, wherein each of the at least one protrusion completely passes through a corresponding through hole of the first pressing piece or a corresponding through hole of the second pressing piece. The cable lead-out system can protect the cable sheaths from being scratched by metal parts.