Invention Grant
- Patent Title: Anticancer trail-targeted plant virus particles
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Application No.: US16614676Application Date: 2018-05-17
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Publication No.: US11672840B2Publication Date: 2023-06-13
- Inventor: Nicole F. Steinmetz
- Applicant: CASE WESTERN RESERVE UNIVERSITY
- Applicant Address: US OH Cleveland
- Assignee: CASE WESTERN RESERVE UNIVERSITY
- Current Assignee: CASE WESTERN RESERVE UNIVERSITY
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- International Application: PCT/US2018/033203 2018.05.17
- International Announcement: WO2018/213587A 2018.11.22
- Date entered country: 2019-11-18
- Main IPC: A61K35/76
- IPC: A61K35/76 ; A61K47/69 ; A61P35/04 ; A61K31/282 ; A61K31/436 ; A61K38/17 ; C12N7/00
Abstract:
An agent is described that includes a plant virus particle or VLP conjugate to TRAIL. Associating TRAIL with the plant virus particle or VLP serves to both target cancer cells and induce their apoptosis. The agent can therefore be used for a method of treating cancer in a subject.
Public/Granted literature
- US20200179468A1 ANTICANCER TRAIL-TARGETED PLANT VIRUS PARTICLES Public/Granted day:2020-06-11
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