Invention Grant
- Patent Title: Soluble bacterial and fungal proteins and methods and uses thereof in inhibiting and dispersing biofilm
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Application No.: US17127911Application Date: 2020-12-18
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Publication No.: US11672846B2Publication Date: 2023-06-13
- Inventor: Lynne P. Howell , Perrin Baker , Noor Alnabelseya , Natalie Bamford , Dustin Little , Donald Sheppard , Brendan Snarr , Mark Jae Lee
- Applicant: The Hospital for Sick Children , The Royal Institution for the Advancement of Learning/McGill University
- Applicant Address: CA Toronto
- Assignee: The Hospital for Sick Children,The Royal Institution for the Advancement of Learning/McGill University
- Current Assignee: The Hospital for Sick Children,The Royal Institution for the Advancement of Learning/McGill University
- Current Assignee Address: CA Toronto; CA Montreal
- Agency: Bereskin & Parr LLP/ S.E.N.C.R.L., s.r.l.
- Agent Melanie Szweras
- Main IPC: C12N9/24
- IPC: C12N9/24 ; A61K38/47 ; A61L29/16 ; A61L27/54 ; A61K45/06 ; A01N63/50 ; A01N63/30 ; A01N63/10 ; A01N63/00 ; A61K35/74 ; A61L27/34 ; A61L29/08 ; A61L31/10 ; A61L31/16
Abstract:
The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.
Public/Granted literature
- US20210138044A1 SOLUBLE BACTERIAL AND FUNGAL PROTEINS AND METHODS AND USES THEREOF IN INHIBITING AND DISPERSING BIOFILM Public/Granted day:2021-05-13
Information query
