Invention Grant
- Patent Title: Bispecific antibody molecules binding to CD3 and TYRP-1
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Application No.: US16721254Application Date: 2019-12-19
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Publication No.: US11672858B2Publication Date: 2023-06-13
- Inventor: Anne Freimoser-Grundschober , Thomas Hofer , Ralf Hosse , Ekkehard Moessner , Valeria G. Nicolini , Pablo Umaña , Inja Waldhauer , Wolfgang Richter , Alexander Knaupp , Halina Trochanowska
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agency: Clark & Elbing, LLP
- Agent Karen L. Elbing
- Priority: EP 214994 2018.12.21
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/30 ; C07K16/28 ; A61P35/00 ; A61K39/00
Abstract:
The present invention generally relates to antibodies that bind to CD3, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
Public/Granted literature
- US20200270347A1 ANTIBODIES BINDING TO CD3 Public/Granted day:2020-08-27
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