Invention Grant
- Patent Title: In vivo immunoimaging of interferon-gamma
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Application No.: US16640456Application Date: 2018-08-23
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Publication No.: US11672877B2Publication Date: 2023-06-13
- Inventor: Nerissa Viola , Heather Gibson
- Applicant: Wayne State University
- Applicant Address: US MI Detroit
- Assignee: Wayne State University
- Current Assignee: Wayne State University
- Current Assignee Address: US MI Detroit
- Agency: Dinsmore & Shohl LLP
- Agent Julie K. Staple
- International Application: PCT/US2018/047742 2018.08.23
- International Announcement: WO2019/040740A 2019.02.28
- Date entered country: 2020-02-20
- Main IPC: A61K51/10
- IPC: A61K51/10 ; C07K16/24

Abstract:
Methods for in vivo immunoimaging including: (a) administering a labeled-antibody conjugate to a subject, wherein the labeled-antibody conjugate includes: an antibody that specifically recognizes and binds to IFN-γ, and a detection label conjugated to the antibody, wherein the detection label is a radionuclide tracer or tluorophore; and (b) detecting the presence of the radiolabeled-antibody conjugate in the subject in vivo by imaging. Embodiments of the present disclosure are directed to labeled-antibody conjugates and therapeutic radionuclide-antibody conjugates.
Public/Granted literature
- US20200206371A1 IN VIVO IMMUNOIMAGING OF INTERFERON-GAMMA Public/Granted day:2020-07-02
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