A data transmission method for use between a wireless transmitter and a wireless receiver of a wireless peripheral device is provided. In a frequency hopping procedure, the wireless transmission data is re-transmitted through a secondary transmission channel. Consequently, a transmission delay problem is reduced. Moreover, the wireless receiver issues a special acknowledgement packet with loadable information to the wireless transmitter. Consequently, the master control power of the frequency hopping procedure is switched from the wireless transmitter to the wireless receiver. In addition, the information control capability of the wireless receiver to control the wireless transmitter in the communication application level can be increased.