An image sensor may include adaptive filtering circuitry that is used to correct for row noise. In one example, the image sensor may include a single reference pixel or a column of reference pixels that are shielded from incident light. The adaptive filtering circuitry may estimate row noise based on data from the reference pixel(s). Row noise correction circuitry may then subtract the estimated row noise from imaging pixel outputs to correct for row noise. If the row noise is dominated by supply noise, the reference pixels may be omitted entirely and the adaptive filtering circuitry may estimate row noise based only on the power supply voltage. The adaptive filtering circuitry may undergo a training phase to optimize coefficients for the adaptive filtering circuitry.