A random access preamble sequence generation method and user equipment are provided. The method includes the following: when receiving first notification signaling sent by a base station, determining, by UE, to calculate a cyclic shift value by using a first solution; obtaining a first logical root sequence number, and determining a root sequence based on the first logical root sequence number; and generating a random access preamble sequence based on the root sequence and the cyclic shift value, where the first solution is a solution of calculating the cyclic shift value when a Doppler shift of the UE is less than a first preset value and greater than a second preset value, the first preset value is less than twice of a physical random access channel (PRACH) subcarrier spacing, the second preset value is greater than the PRACH subcarrier spacing.