The present disclosure relates to the field of display technology, and describes a pixel driving circuit detection method, a display panel, a driving method thereof, and a display device. The detection method includes inputting a reference voltage to the data line during at least part of the initial phase; turning on the first and second switch sub-circuits during the charging phase, to input the detection voltage to the data line, while inputting the reset voltage to the sensing line; turning on the second switch sub-circuit during the charging phase, to input the driving current by the driving transistor to the sensing line under the effect of the detection voltage; turning off the first and second switch sub-circuits during the detection phase, to detect the voltage on the sensing line; and obtaining the mobility of the driving transistor according to the voltage on the sensing line detected in the detection phase.