Invention Grant
- Patent Title: Separation matrix
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Application No.: US17221438Application Date: 2021-04-02
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Publication No.: US11685764B2Publication Date: 2023-06-27
- Inventor: Gustav José Rodrigo , Tomas Bjorkman , Mats Ander , Jesper Ulf Hansson
- Applicant: Cytiva BioProcess R&D AB
- Applicant Address: SE Uppsala
- Assignee: CYTIVA BIOPROCESS R&D AB
- Current Assignee: CYTIVA BIOPROCESS R&D AB
- Current Assignee Address: SE Uppsala
- Agency: Eversheds Sutherland (US) LLP
- Priority: GB 08229 2016.05.11 GB 08232 2016.05.11
- Main IPC: A23J1/00
- IPC: A23J1/00 ; C07K1/22 ; B01D15/38 ; B01J20/24 ; B01J20/28 ; B01J20/286 ; B01J20/32 ; C07K14/31 ; C07K16/00 ; C07K16/06 ; C07K17/10
Abstract:
The invention relates to a separation matrix comprising at least 11 mg/ml Fc-binding ligands covalently coupled to a porous support, wherein:
a) the ligands comprise multimers of alkali-stabilized Protein A domains, and
b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50, v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.
a) the ligands comprise multimers of alkali-stabilized Protein A domains, and
b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50, v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.
Public/Granted literature
- US20210221841A1 Separation Matrix Public/Granted day:2021-07-22
Information query
