A system and method of controlling iguana infestation is provided. The system and method, being harmless to people and pets, can include a wall barrier, sea barrier, ground barrier, and climbing (tree, piling) barrier. The iguana sea wall barrier prevents iguanas from accessing property from the water. Iguana piling wraps can be included to prohibit access to the property via the dock. Iguana tree guards can be included to prevent iguanas from climbing up into trees.