Invention Grant
- Patent Title: Folate salts for medical use
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Application No.: US16651688Application Date: 2018-08-29
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Publication No.: US11690846B2Publication Date: 2023-07-04
- Inventor: Martin Ulmann , Gerd Wiesler , Arthur Bodenmüller , Markus Müller
- Applicant: APROFOL AG
- Applicant Address: CH Appenzell Steinegg
- Assignee: APROFOL AG
- Current Assignee: APROFOL AG
- Current Assignee Address: CH Appenzell Steinegg
- Agency: Nguyen Tarbet LLC
- Priority: EP 020449 2017.09.29
- International Application: PCT/EP2018/073280 2018.08.29
- International Announcement: WO2019/063236A 2019.04.04
- Date entered country: 2020-03-27
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/53

Abstract:
The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)-tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin and phenylethylbiguanidin. The cation is an organic compound with a complementary pharmacological activity.
Public/Granted literature
- US20200261460A1 FOLATE SALTS FOR MEDICAL USE Public/Granted day:2020-08-20
Information query
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