Invention Grant
- Patent Title: Alkoxy pyrazoles as soluble guanylate cyclase activators
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Application No.: US17258759Application Date: 2019-07-09
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Publication No.: US11690848B2Publication Date: 2023-07-04
- Inventor: Judith Ertle , Jochen Huber , Ruediger Streicher
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent David L. Kershner
- International Application: PCT/EP2019/068448 2019.07.09
- International Announcement: WO2020/011804A 2020.01.16
- Date entered country: 2021-01-08
- Main IPC: A61K31/5395
- IPC: A61K31/5395 ; A61K31/44 ; A61K31/4725 ; A61K31/55

Abstract:
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6 and R7 are as defined herein, for use in the treatment of diseases or disorders that can be alleviated by sGC activation or potentiation, selected from chronic liver diseases, Non-Alcoholic Steatohepatitis (NASH), cirrhosis and portal hypertension.
Public/Granted literature
- US20210121473A1 Alkoxy Pyrazoles as Soluble Guanylate Cyclase Activators Public/Granted day:2021-04-29
Information query
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