Filter media includes a filtration substrate having a first side and a second side, and constructed for filtering a fluid by flow of the fluid therethrough. The filtration substrate has a machine direction extending from a first end to a second end, and a cross direction extending from a first edge to a second edge. The filtration substrate includes a plurality of corrugations extending in the machine direction. The plurality of corrugations include a plurality of first crests formed along the first side and a plurality of second crests formed along the second side. The filtration substrate includes a plurality of bosses along the plurality of first crests or along the plurality of second crests and extending in a direction away from the other of the plurality of first crests or the plurality of second crests. Media packs, filter elements, and methods of making are provided.