Disclosed are systems and methods for dynamically re-routing a pick path to an alternate pick location in response to identifying a shorted product at a pick location. The dynamic decision to re-route an autonomous vehicle is based on completion scores representing a likelihood of completing order in an autonomous vehicle, a maximum remaining time, an additional pick time, and order priorities. Based on various weights for factors of the orders, a system may re-route the autonomous vehicle to fulfill a shorted order at an alternate location when no orders have a high likelihood of completion, the additional pick time associated with re-routing the autonomous vehicle to the alternate pick location is less than the maximum remaining time for each order on the autonomous vehicle, and/or none of the orders on the autonomous vehicle have a higher priority than the shorted order.